Omicron - How Bad Is It?

NEW VARIANT Omicron - How Bad Is It?

There is a lot of concern about more than 50 mutations in the new SARS-COV-2 variant. WHO has dubbed it variant of concern and named it Omicron. Let's see if it can be more contagious, deadly, and will escape our existing immunity due to previous infection or vaccines.

The fifteenth letter of the Greek alphabet.

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References

Mutations: G142D/Δ143-145, Δ211/L212I, ins214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493K, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H, N764K, D796Y, N856K, Q954H, N969K, L981F

Conserved non-Spike mutations - NSP3 – K38R, V1069I, Δ1265/L1266I, A1892T; NSP4 – T492I; NSP5 – P132H; NSP6 – Δ105-107, A189V; NSP12 – P323L; NSP14 – I42V; E – T9I; M – D3G, Q19E, A63T; N – P13L, Δ31-33, R203K, G204R

WHO https://www.who.int/news/item/26-11-2021-classification-of-omicron-(b.1.1.529)-sars-cov-2-variant-of-concern
GISAID: https://www.gisaid.org/hcov19-variants/
NY Times. Great article: https://www.nytimes.com/2021/11/26/health/omicron-variant-vaccines.html
About the changes: https://www.worldofmolecules.com/3D/B.1.1.529-variant.html
https://ourworldindata.org/coronavirus/country/south-africa
https://ourworldindata.org/grapher/biweekly-growth-covid-cases?tab=chart&country=~ZAF
https://www.sciencedirect.com/science/article/pii/S2001037021004268
https://nextstrain.org/ncov/gisaid/global?c=emerging_lineage
https://www.gisaid.org/
https://www.gisaid.org/hcov19-variants/
https://www.pnas.org/content/118/43/e2100943118
https://en.wikipedia.org/wiki/Omicron


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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.