'SNL': Woody Harrelson hosts and takes jab at COVID; Cold open spoofs Trump's Ohio visit | USA TODAY

Woody Harrelson took aim at COVID vaccine mandates during his return to "Saturday Night Live."

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Harrelson, 61, closed out his opening monologue Saturday discussing the "craziest script" he's ever read.

"So the movie goes like this… The biggest drug cartels in the world get together and buy up all the media and all the politicians and force all the people in the world to stay locked in their homes," he said. "And people can only come out if they take the cartel’s drugs and keep taking them over and over."

In the show's cold open, former President Donald Trump's visit to East Palestine, Ohio, following the toxic train derailment.

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